Thursday, February 13, 2020

Cellular Enviroment Assignment Example | Topics and Well Written Essays - 500 words

Cellular Enviroment - Assignment Example 16-17). According to McCance & Huether (2010), cellular swelling is the initial sign of cell injury; triggered by direct damage to the cell membrane, hypoxia, or damage to the electrolyte-pumping enzymes. The most common cause of cellular injury is hypoxia, which disrupts the cell’s capability of maintaining fluid homeostasis due to deficiency in oxygen. The main cellular mechanisms of cell injury include loss of calcium homeostasis, ATP depletion, oxidative stress, damage to mitochondria, and increases permeability of membranes. These adaptive mechanisms thus fail to maintain normal homeostasis, leading to a fall in oxidative phosphorylation. This triggers the depletion of cellular ATP and the swelling of mitochondria. What follows next is the failure of membrane calcium pumps, protein synthesis, NaK ATPase pump, and generation of reactive oxygen metabolites. This leads to an influx of Na+ and water, efflux of K+, entry of free calcium into the cytoplasm, and a drop in intracellular pH. This results to accumulation of water into the cell triggered by failure of membrane NaK ATPase pump, and cellular swelling due to swelling of endoplasmic reticulum (p. 54-92). Cellular swelling during the early stages is a reversible lesion, which is non-lethal; however, it becomes reversible if hypoxia persists for some time depending on the oxygen demands of the cell. An irreversible injury leads to cell death, mainly via apoptosis or necrosis. Aging is a gradual deterioration of a mature organism leading to irreversible structural changes as time passes by. According to Brashers (2006), cellular changes facets of aging include hypertrophy, and the weakened capability to undergo mitosis. Cellular function is impaired by the deposition of lipids (lipid peroxidation products), programmed changes in gene expression, damage from free radicals and advanced glycation end products. These

Saturday, February 1, 2020

Strategic Choice Essay Example | Topics and Well Written Essays - 1000 words

Strategic Choice - Essay Example Growth relates to each and every employee at the workplace. The development in the quality of existing employees’ skills and the quantity of skilled workers leads to overall organizational growth. The most precious asset that a company may cherish is its employees and it needs to be seriously concerned with all issues that may dissatisfy, frustrate or depress them. Without happy employees, no strategy is going to work and no progress will be seen in the long run. This paper discusses what alternative my organization (Human-Care.org) must consider to realize growth and what strategy or combination of generic and grand strategies it must implement in order to improve its organizational growth. Alternative Strategies Leading to Organizational Growth Human-Care.org pursues its organizational growth, growth stages and the directions in which the company is going in a variety of ways. Yet, it is undergoing some troubles regarding guiding itself and its labor through periods of growth. It is having problems with maintaining control over resources and workforce. There are many recommendations and alternatives that it needs to consider to chase the course of its growth at every stage. Some of these strategies are discussed below: 1. New Markets and Target Consumers ... 2. New Services The organization should also try to offer new services to the consumers apart from simply recording and filing their complaints. When it will expand its offers to the clients, it will automatically attract more clientele and build its repertoire in the market and among the competitors. Implementation of new products and services is recognized as a significant way leading to organizational growth. 3. Looking for External Financial Resources We are focusing significantly on increasing the finances because we know that the organization will need funds to support its expansion in terms of employees and resources. A productive way to increase this funding is to look for external financial resources which may be in the form of monitory support from investors, partnerships, banks, and other government and private companies that may want to acquire the organization and fund it. This funding will help the company in designing and implementing such generic and grand strategies that ensure its growth. Growth Strategies for my Organization A strategy means a plan that guides an organization through a process or from one state to another. A growth strategy is the plan that the organization uses to broaden the scope of its business by expanding its consumer group. The objective of such a strategy is to improve the organizational growth while balancing the resources at the same time. Although there are many kinds of growth strategies that firms use like merger, joint venture, acquisition, and strategic alliance, I would recommend that Human-Care.org must use the joint venture and strategic alliance strategies to enhance its organizational growth.